Intrauterine insemination in Egypt


What is intrauterine insemination ?

Intrauterine insemination performed in Egypt is a technique for medically assisted procreation. Its aim is to facilitate the meeting of gametes (sperm and eggs) in order to increase the chances of fertilization and pregnancy in an infertile couple.
Its principle is based on the direct injection of sperm from the partner (Insemination with partner sperm) or from a donor (Insemination with donor sperm) into the uterine cavity during the peri-ovulatory period.

How much does an intrauterine insemination cost ?

To have the price of an intrauterine insemination realized in Egypt, you will have to ask for a free online quote to obtain the cost of this procedure or you can contact us by phone and one of our counselors will answer all your questions.

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The indications

Intrauterine insemination in Egypt is indicated after an infertility check-up of the couple :

  • Moderate abnormalities of the sperm revealed by a spermogram with spermocytogram (with at least 1 million motile and progressive spermatozoa)
  • Mechanical or psychic disorders of ejaculation or sexual relations (malformations, neurological pathologies, impotence etc.)
  • Anomaly of the cervix (malformation, obstruction after laser treatment or after conization) or cervical mucus hindering the passage of sperm
  • Repeated failure to stimulate ovulation especially with a negative Hühner test (post-coital test)
  • Idiopathic sterility
  • Ovarian insufficiency
  • Mild endometriosis
  • IVF failure or conversion.
  • Insemination with donor sperm is an option taken by some couples when the partner has azoospermia (absence of sperm) : in the case of repeated failures of micro-injections (I.C.S.I.) in connection with severe sperm abnormalities or in the case of certain hereditary diseases in men.
  • Insemination with thawed semen is an option used when it is not possible to collect fresh semen from the spouse on the day of the insemination (impotence problems...).

For whom intrauterine insemination is not recommended ?

Intrauterine insemination (IUI) may not be recommended or suitable for certain individuals or couples depending on various factors. Here are some scenarios where IUI might not be the best option :

  1. Severe male factor infertility : If the male partner has severe sperm abnormalities such as very low sperm count, poor sperm motility, or abnormal sperm morphology, IUI may not be effective.
  2. Blocked fallopian tubes : If the woman has blocked or severely damaged fallopian tubes, IUI may not be successful because it relies on the natural ability of sperm to swim through the fallopian tubes to reach the egg. In such cases, IVF may be a better option because it bypasses the fallopian tubes altogether.
  3. Severe endometriosis : Endometriosis can interfere with fertility by causing inflammation, scarring, and blockage of the fallopian tubes. In cases of severe endometriosis, where natural conception is unlikely, IVF may be recommended over IUI.
  4. Advanced age : For women over a certain age (typically over 35-40), especially if there is a significant decline in ovarian reserve or other fertility issues, the success rates of IUI may be lower. In such cases, IVF with or without donor eggs may offer better chances of success.
  5. Unexplained infertility after multiple attempts : If a couple has undergone several unsuccessful IUI cycles without identifying a specific cause of infertility, it may indicate that IUI is not the most effective treatment option. In such cases, a reevaluation of the couple's fertility status and consideration of alternative treatments like IVF may be warranted.
  6. Certain medical conditions : Certain medical conditions such as severe uterine abnormalities, untreated pelvic infections, or certain genetic disorders may make IUI unsuitable or less effective. It is important for individuals with such conditions to consult a fertility specialist to determine the most appropriate treatment options.

Ultimately, the decision about whether IUI is the right option depends on individual factors such as the cause of infertility, the age of the individuals involved in this procedure, and their medical history. It is essential for couples to undergo a thorough evaluation by a fertility specialist to determine the most appropriate treatment plan for their specific situation.

Check-up before an intrauterine insemination

Before intrauterine insemination performed in Egypt, a preliminary check-up is carried out on both members of the couple. It includes :

For women :

  • A clinical examination (examination of the uterus, cervico-vaginal smear, pelvic ultrasound)
  • A hormonal check-up
  • Serologies (Toxoplasmosis, Rubella, AIDS, Syphilis, Hepatitis B, Hepatitis C). They are valid for a period of three months for a first attempt and twelve months for any subsequent attempt
  • A hysterosalpingography in order to ensure the permeability of the fallopian tubes (at least one permeable tube).

For men :

  • A clinical examination
  • Serologies (AIDS, Syphilis, Hepatitis B, Hepatitis C, Chlamydia). They are valid for a period of three months for a first attempt and twelve months for any subsequent attempt
  • A spermogram, spermocytogram, survival migration test and a sperm culture (recent, less than six months old).

How is it performed ?

Each treatment cycle consists of three successive phases :

  • Stimulation of the ovulation : the stimulation of ovulation by only gonadotrophins or combined with Clomiphene Citrate aims at obtaining one to three follicles in order to increase the chances of pregnancy and to synchronize the insemination itself with the period of maximum fertility (ovulatory period). The stimulation is combined with ovulation monitoring.
  • Triggering ovulation : this is usually done by an injection of HCG in the evening. This injection makes it possible to ovulate one or more mature follicles 36 to 40 hours later. It is important to trigger ovulation at the right time when the follicles reach a size of 17 to 18 mm, their number is ≤ 3 (in order to avoid a high-ranking multiple pregnancy) and the estradiol level is around 250 pg/ml per mature follicle. A thickness of the endometrium of more than 8 mm on the day of triggering gives a better chance of embryonic implantation.
  • Intrauterine insemination : this takes place the day after triggering ovulation in the morning. The sperm is collected from the spouse in the morning in a specialized laboratory. A prior abstinence period of 3 to 5 days is recommended. The sperm is analyzed and then prepared by the medical biologist. It is then placed in a small vial and transported rapidly to the place of insemination.

During a simple gynaecological consultation, the gynaecologist places the prepared sperm in a fine, flexible catheter. He then introduces this catheter into the patient's uterine cavity which is located in the gynaecological position, through the speculum, via the natural channels. The catheter is removed and the patient remains lying down for about ten minutes. The procedure is completely painless.
After insemination, the patient can resume normal activity. Sexual intercourse on the day of the insemination or the following day may slightly increase the chances of success.
Insemination can be performed with donor sperm or with thawed sperm.
In some cases, the sperm is injected into the cervix (intra-cervical insemination).

After intrauterine insemination

A pregnancy blood test is realized two weeks after intrauterine insemination realized in Egypt in case of delayed menstruation. It is repeated 48 hours later in case of a positive result. A first ultrasound scan is recommended at 4 weeks of pregnancy (or 6 weeks of amenorrhea) to check the correct location of the pregnancy.
In the case of repeated failures, the couple may opt for in vitro fertilization (IVF) or microinjection.

What are the advantages of intrauterine insemination ?

Intrauterine insemination (IUI) offers several advantages for couples experiencing fertility issues :

  1. Non-invasive procedure : IUI is less invasive compared to other assisted reproductive technologies like in vitro fertilization (IVF). It involves placing washed and concentrated sperm directly into the uterus, bypassing the cervix, which can be helpful for couples with cervical issues.
  2. Increased sperm concentration : By concentrating sperm and placing it directly into the uterus, IUI increases the number of sperm cells that are available to fertilize the egg, thus improving the chances of conception.
  3. Timing control : IUI allows for precise timing of sperm delivery with ovulation, increasing the likelihood of sperm being present in the fallopian tubes when the egg is released. This timing can be crucial for couples with timing-related fertility issues.
  4. Cost-effectiveness : Compared to more complex ART procedures like IVF, IUI is generally more affordable. This makes it a preferable option for couples who may not require more advanced treatments.
  5. Minimal side effects : IUI involves minimal medication and has fewer side effects compared to more invasive procedures like IVF. This can lead to a more comfortable experience for patients.
  6. Suitable for certain fertility issues : IUI can be effective for couples with mild male factor infertility, unexplained infertility, or cervical issues. It can also be a good option for single women or same-sex couples who require sperm donation to conceive.
  7. Less stressful : Since IUI is a relatively simple procedure that can often be performed in a doctor's office, it tends to be less stressful for patients compared to more complex ART treatments that require multiple clinic visits and invasive procedures.

However, it is important to note that the success rates of IUI can vary depending on various factors such as the age of the woman, the cause of infertility, and the quality of sperm. It is essential for couples to consult a fertility specialist to determine if IUI is the best option for their specific situation.

What activities should be avoided after intrauterine insemination ?

After intrauterine insemination (IUI), it is generally recommended to avoid certain activities to optimize the chances of successful implantation and pregnancy. Here are some common recommendations :

  1. Intense physical activity : While light exercise is usually considered safe after IUI, it is generally advised to avoid intense physical activities such as heavy lifting, vigorous exercise, or high-impact sports. Strenuous activities may increase the risk of uterine contractions or displacement of the embryos, potentially reducing the chances of successful implantation.
  2. Sexual intercourse : Some fertility specialists recommend abstaining from sexual intercourse for a brief period after IUI to allow the sperm to remain in the uterus and increase the chances of fertilization. However, guidelines on this may vary, and your doctor will provide specific instructions based on your individual circumstances.
  3. Hot tubs or saunas : Exposure to high temperatures, such as those in hot tubs, saunas, or hot baths, should be avoided after IUI. Elevated body temperatures can potentially interfere with embryo implantation and early pregnancy development.
  4. Alcohol and tobacco : It is advisable to avoid alcohol and tobacco after IUI, as they can have negative effects on fertility and pregnancy outcomes. Both alcohol and tobacco can impair fertility and increase the risk of complications during pregnancy.
  5. Stressful situations : While it is not always possible to avoid stress completely, it is beneficial to minimize exposure to stressful situations as much as possible after IUI. Stress can have a negative impact on fertility and may affect the chances of successful implantation and pregnancy.
  6. Certain medications and herbal supplements : It is essential to consult your doctor about any medications or herbal supplements you're taking, as some may interfere with fertility treatments or early pregnancy. Your doctor will provide guidance on which medications are safe to continue and which should be avoided.

It is important to follow the specific instructions provided by your fertility specialist after IUI, as recommendations may vary depending on individual circumstances and medical history. If you have any questions or concerns about post-IUI activities, don't hesitate to discuss them with your healthcare provider.